Share

Dr Simon Richardson(Nanowerk News) February 25, 2010 - A team of scientists led by Dr Simon Richardson at the University of Greenwich has got a step closer to one of the holy grails of drug delivery. The goal – to find a vehicle that can carry drugs not just to a specific cell but a specific organ (organelle) inside the cell, and accurately measure how it behaves when it gets there – has proved elusive despite two decades of research, according to the Journal of Controlled Release ("Intracellular fate of bioresponsive poly(amidoamine)s in vitro and in vivo").

Now the journal has given the new research front page billing, saying in an editorial that Richardson and colleagues provide direct evidence, for the first time, that nanomedicines can be delivered to select organelles and manipulated to carry beneficial agents like genes. Dr Richardson says: “Drug delivery is important for everyone because it has the potential to deliver new treatments for diseases which are currently incurable; and to deliver existing drugs more effectively.”

Source/read more